gene

RPS3A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about RPS3A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

3Connections

0Hypotheses

0Analyses

2Outgoing

1Incoming

0Experiments

0Debates

Summary

Comprehensive overview of RPS3A (ribosomal protein S3a), a component of the 40S ribosomal subunit with roles in translation, DNA repair, and apoptosis, implicated in Diamond-Blackfan anemia and neurodegenerative diseases.

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🧬 Gene Info

Gene Symbol	RPS3A
Full Name	Ribosomal Protein S3a
Chromosome	19p13.3
Function	is a member of the ribosomal protein S3 family and is highly conserved across eukaryotes.
Amino Acids	271 aa
UniProt ID	P23368
NCBI Gene ID	6208
Ensembl ID	ENSG00000144040
OMIM	603012
GeneCards	RPS3A
Human Protein Atlas	RPS3A
Associated Diseases	neurodegeneration
Interactions	TREK1
KG Connections	3 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: RPS3A — AlphaFold P23368 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

RPS3A — Ribosomal Protein S3a

gene · 1210 words

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Pathway Diagram

graph TD
    RPS3A["RPS3A"]
    SUMO(["SUMO"])
    TREK1(["TREK1"])
    MHV68["MHV68"]
    neurodegeneration["neurodegeneration"]

    RPS3A -->|"binds"| SUMO
    RPS3A -->|"interacts with"| TREK1
    MHV68 -->|"interacts with"| RPS3A
    RPS3A -->|"implicated in"| neurodegeneration

    style RPS3A fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style SUMO fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
    style TREK1 fill:#1a237e,stroke:#4fc3f7,stroke-width:2px,color:#fff
    style MHV68 fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff
    style neurodegeneration fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (2)

Target	Relation	Type	Str
SUMO	binds	protein	0.80
TREK1	interacts_with	protein	0.70

Incoming (1)

Source	Relation	Type	Str
MHV68	interacts_with	entity	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning RPS3A in their description or question text

No additional research found