Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPS2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Gene Symbol | RPS2 |
| Full Name | Ribosomal Protein S2 |
| Chromosome | 16p13.3 |
| Function | encodes a ribosomal protein that is a critical component of the 40S small ribosomal subunit. |
| Primary Expression | both neurons and glial cells |
| Subcellular Localization | the cell body and dendrites, where it supports local protein synthesis at synaptic sites [10](https://pubmed.ncbi.nlm.ni |
| Molecular Weight | 23 kDa |
| Amino Acids | 194 aa |
| UniProt ID | P43307 |
| NCBI Gene ID | 6198 |
| GeneCards | RPS2 |
| Human Protein Atlas | RPS2 |
| High Expression | Brain, liver, kidney, and tissues with high protein synthetic activity |
| Moderate Expression | Heart, muscle, and other metabolic tissues |
| Lower Expression | Adipose tissue and some peripheral tissues |
| Associated Diseases | neurodegeneration |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["RPS2"]
N1["RPS18"]
N1 -->|"upregulates"| N0
N2["neurodegeneration"]
N0 -->|"implicated in"| N2
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 gene| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| RPS18 | upregulates | gene | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RPS2 in their description or question text
No additional research found