Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about RPL29: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | RPL29 |
| Full Name | Ribosomal Protein L29 |
| Function | 60S subunit component: Part of the large ribosomal subunit |
| Amino Acids | 159 aa |
| UniProt ID | P47914 |
| Ensembl ID | ENSG00000137285 |
| GeneCards | RPL29 |
| Human Protein Atlas | RPL29 |
| Protein synthesis | Essential for translation of mRNA into protein |
| Ribosome assembly | Participates in the assembly of functional ribosomes |
| Cellular localization | Cytoplasmic and nucleolar (during assembly) |
| RPL5, RPL11 | Core 60S proteins |
| RPL23 | Neighboring ribosomal proteins |
| eIF4E | Translation initiation factor |
| Translation impairment | Global reduction in protein synthesis in AD brain 2 |
| Associated Diseases | neurodegeneration |
| Interactions | CANCER, CREBBP, EP300, MYC, RPL36 |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
RPL29["RPL29"]
Ms{"Ms"}
RPL29 -->|"inhibits"| Ms
Cancer{"Cancer"}
RPL29 -->|"inhibits"| Cancer
RPL36["RPL36"]
RPL29 -->|"inhibits"| RPL36
MYC["MYC"]
RPL29 -->|"inhibits"| MYC
CANCER["CANCER"]
RPL29 -->|"inhibits"| CANCER
EP300["EP300"]
RPL29 -->|"inhibits"| EP300
CREBBP["CREBBP"]
RPL29 -->|"inhibits"| CREBBP
neurodegeneration["neurodegeneration"]
RPL29 -->|"implicated in"| neurodegeneration
style RPL29 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning RPL29 in their description or question text
No additional research found