Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PUFA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| Cyclooxygenases | associated_with | enzyme | 0.70 |
| FERROPTOSIS | activates | phenotype | 0.64 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ACC | regulates | gene | 0.56 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| ALOX15-Driven Enzymatic Ferroptosis in AD Oligodendrocytes v | 0.777 | Alzheimer's Disease | Cell type vulnerability in Alzheimers Di |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| Bioinformatics analysis and hub gene identification | exploratory | Alzheimer's disease | 0.800 | 0.00 | computational analysis of tran | proposed | N/A |
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| Inflammatory Processes in Alzheimer's Disease-Pathomechanism, Diagnosis and Trea [PMID:37047492] | Unknown | Int J Mol Sci | 2023 | 0 |
| Pathogenesis of Alzheimer's Disease. [PMID:36613544] | Unknown | Int J Mol Sci | 2022 | 0 |
| Alzheimer's disease. [PMID:31753135] | ["Soria Lopez, Jose A", "Gonz\u00e1lez, | Handbook of clinical neurology | 2019 | 0 |
| Alzheimer's disease. [PMID:28872215] | ["Lane, C A", "Hardy, J", "Schott, J M"] | European journal of neurology | 2018 | 0 |
| Current understanding of Alzheimer's disease diagnosis and treatment. [PMID:30135715] | ["Weller, Jason", "Budson, Andrew"] | F1000Research | 2018 | 0 |
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning PUFA in their description or question text
No additional research found