Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about OSIMERTINIB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | OSIMERTINIB |
| Key Genes/Proteins | EGFR, IL6 |
| Related Diseases | CANCER, DRUG RESISTANCE, LUNG CANCER, TUMOR MICROENVIRONMENT |
graph TD
OSIMERTINIB[OSIMERTINIB]
OSIMERTINIB -->|target for| EGFR[EGFR]
EGFR -->|targets| OSIMERTINIB
CANCER[CANCER] -->|treats| OSIMERTINIB| Target | Relation | Type | Str |
|---|---|---|---|
| EGFR | therapeutic_target | gene | 0.90 |
| EGFR | inhibits | protein | 0.70 |
| EGFR | activates | gene | 0.65 |
| IL6 | associated_with | gene | 0.45 |
| LUNG CANCER | associated_with | disease | 0.45 |
| EGFR | associated_with | gene | 0.45 |
| CANCER | associated_with | disease | 0.45 |
| TUMOR CELLS | associated_with | cell_type | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| EGFR | targets | gene | 0.90 |
| CANCER | inhibits | disease | 0.65 |
| CANCER | treats | disease | 0.65 |
| CANCER | activates | disease | 0.65 |
| CANCER | associated_with | disease | 0.45 |
| TUMOR MICROENVIRONMENT | associated_with | phenotype | 0.45 |
| IL6 | associated_with | gene | 0.45 |
| LUNG CANCER | associated_with | disease | 0.45 |
| EGFR | associated_with | gene | 0.45 |
| DRUG RESISTANCE | associated_with | phenotype | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning OSIMERTINIB in their description or question text
No additional research found