gene

NETO2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NETO2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

0Outgoing

2Incoming

0Experiments

0Debates

Summary

NETO2 — Neuropilin and Tolloid Like 2

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🧬 Gene Info

Gene Symbol	NETO2
Full Name	Neuropilin And Tolloid Like 2
Function	NETO2 (Neuropilin and Tolloid Like 2) is a transmembrane protein that plays important roles in synaptic function, neurodevelopment, and cell signaling.
Primary Expression	the central nervous system and participates in the regulation of glutamate receptor trafficking and synaptic plasticity[@little2010]
UniProt ID	Q9H6X4
Ensembl ID	ENSG00000167037
GeneCards	NETO2
Human Protein Atlas	NETO2
Associated Diseases	neurodegeneration
Interactions	AKT1, MAPK1
KG Connections	2 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: NETO2 — AlphaFold Q9H6X4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

NETO2 — Neuropilin and Tolloid Like 2

gene · 576 words

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Pathway Diagram

graph TD
    NETO2["NETO2"]
    neurodegeneration["neurodegeneration"]
    NETO2 -->|"implicated in"| neurodegeneration
    AKT1["AKT1"]
    AKT1 -->|"activates"| NETO2
    MAPK1["MAPK1"]
    MAPK1 -->|"activates"| NETO2
    style NETO2 fill:#1a237e,stroke:#4fc3f7,color:#4fc3f7

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (2)

Source	Relation	Type	Str
AKT1	activates	gene	0.70
MAPK1	activates	gene	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NETO2 in their description or question text

No additional research found