Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Microglial Survival: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| TREM2 | activates | protein | 0.90 |
| TREM2 Agonistic Antibodies | activates | drug | 0.90 |
| TREM2 | modulates | protein | 0.90 |
| TREM2 Agonistic Antibodies | enhances | drug | 0.90 |
| TREM2 | protective_against | gene | 0.90 |
| Trem2 | associated_with | protein | 0.90 |
| CSF-1R pathway | regulates | pathway | 0.70 |
| BCL2L1 | regulates | gene | 0.70 |
| TREM2 | regulates | gene | 0.70 |
| TREM2 agonistic antibodies | activates | drug | 0.70 |
| TREM2 | regulates | gene | 0.70 |
| PI3K-Akt | regulates | pathway | 0.70 |
| TREM2 | promotes | gene | 0.70 |
| CSF1R | maintains | gene | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-17 | 7 hypotheses Top: 0.685
neurodegeneration | 2026-04-16 | 1 hypotheses Top: 0.627
neurodegeneration | 2026-04-16 | 4 hypotheses Top: 0.887
neuroimmunology | 2026-04-15 | 1 hypotheses Top: 0.670
molecular biology | 2026-04-12 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.59 · 2026-04-27
closed · Rounds: 4 · Score: 0.21 · 2026-04-27
closed · Rounds: 4 · Score: 0.68 · 2026-04-22
closed · Rounds: 4 · Score: 0.82 · 2026-04-22
closed · Rounds: 4 · Score: 0.30 · 2026-04-21
closed · Rounds: 4 · Score: 0.30 · 2026-04-21
closed · Rounds: 4 · Score: 0.50 · 2026-04-20
closed · Rounds: 4 · Score: 0.50 · 2026-04-18
closed · Rounds: 4 · Score: 0.50 · 2026-04-18
closed · Rounds: 4 · Score: 1.00 · 2026-04-18
Hypotheses and analyses mentioning Microglial Survival in their description or question text
No additional research found