gene

MYH7

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MYH7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

8Connections

0Hypotheses

0Analyses

7Outgoing

1Incoming

0Experiments

0Debates

Summary

Myosin Heavy Chain 7 - a motor protein with roles in muscle function and emerging connections to neurodegeneration

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🧬 Gene Info

Gene Symbol	MYH7
Aliases	Myosin Heavy Chain 7
Chromosome	14q11.2
Function	encodes a protein of 1935 amino acids that forms part of the myosin II heavy chain.
Primary Expression	Cardiac muscle, slow-twitch skeletal muscle
Amino Acids	1935 aa
Pathways	Angiogenesis, Dna Methylation, Epigenetic
UniProt ID	P12883
NCBI Gene ID	4625
Ensembl ID	ENSG00000092096
OMIM	160760
GeneCards	MYH7
Human Protein Atlas	MYH7
Associated Diseases	Alzheimer's disease, Parkinson's disease
Interactions	CREB5, FOXO3
KG Connections	8 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: MYH7 — AlphaFold P12883 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

MYH7 Gene

gene · 1437 words

→

Pathway Diagram

graph TD
    MYH7["MYH7"]
    Als{"Als"}
    MYH7 -->|"regulates"| Als
    Ms{"Ms"}
    MYH7 -->|"regulates"| Ms
    FOXO3["FOXO3"]
    MYH7 -->|"activates"| FOXO3
    EXERCISE["EXERCISE"]
    MYH7 -->|"regulates"| EXERCISE
    Epigenetic(["Epigenetic"])
    MYH7 -->|"regulates"| Epigenetic
    Dna_Methylation(["Dna Methylation"])
    MYH7 -->|"regulates"| Dna_Methylation
    Angiogenesis(["Angiogenesis"])
    MYH7 -->|"regulates"| Angiogenesis
    neurodegeneration["neurodegeneration"]
    MYH7 -->|"implicated in"| neurodegeneration
    CREB5["CREB5"]
    CREB5 -->|"activates"| MYH7
    style MYH7 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (7)

Target	Relation	Type	Str
Als	regulates	disease	0.65
Ms	regulates	disease	0.65
EXERCISE	regulates	gene	0.60
Epigenetic	regulates	pathway	0.60
Dna Methylation	regulates	pathway	0.60
Angiogenesis	regulates	pathway	0.60
FOXO3	activates	gene	0.60

Incoming (1)

Source	Relation	Type	Str
CREB5	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MYH7 in their description or question text

No additional research found