Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about IL5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | IL5 |
| Chromosome | 5q31.1 |
| Protein Type | Th2 cytokine |
| Function | IL-5 has specialized functions in eosinophil biology: |
| Molecular Weight | 15 kDa |
| Pathways | PI3K, MAPK |
| NCBI Gene ID | 3569 |
| GeneCards | IL5 |
| Human Protein Atlas | IL5 |
| Associated Diseases | neurodegeneration |
| Interactions | ADORA2B, FN1, INFLAMMATION, OCLN |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
IL5["IL5"]
Als{"Als"}
IL5 -->|"inhibits"| Als
Inflammation{"Inflammation"}
IL5 -->|"inhibits"| Inflammation
FN1["FN1"]
IL5 -->|"inhibits"| FN1
OCLN["OCLN"]
IL5 -->|"inhibits"| OCLN
neurodegeneration["neurodegeneration"]
IL5 -->|"implicated in"| neurodegeneration
ADORA2B["ADORA2B"]
ADORA2B -->|"inhibits"| IL5
INFLAMMATION["INFLAMMATION"]
INFLAMMATION -->|"inhibits"| IL5
style IL5 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Als | inhibits | disease | 0.65 |
| Inflammation | inhibits | disease | 0.65 |
| FN1 | inhibits | gene | 0.60 |
| OCLN | inhibits | gene | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ADORA2B | inhibits | gene | 0.60 |
| INFLAMMATION | inhibits | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning IL5 in their description or question text
No additional research found