Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HSP27PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Hsp27 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
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| Gene Symbol | HSP27PROTEIN |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 27 kDa |
| GeneCards | HSP27PROTEIN |
| Human Protein Atlas | HSP27PROTEIN |
| N-terminal domain | Contains the WDPF motif for oligomerization |
| Alpha-crystallin domain | Conserved region shared with alpha-crystallins |
| C-terminal region | Flexible tail involved in substrate binding |
| Associated Diseases | ALS, neurodegeneration |
| Interactions | ALS, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, Amyloid-Beta, AMYLOID-BETA |
| KG Connections | 151 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
HSP27PROTEIN["HSP27PROTEIN"]
neurodegeneration["neurodegeneration"]
HSP27PROTEIN -->|"implicated_in"| neurodegeneration
style HSP27PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning HSP27PROTEIN in their description or question text
No additional research found