Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GUT MICROBIOTA DYSBIOSIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GUT MICROBIOTA DYSBIOSIS |
Knowledge base pages for this entity
graph TD
GUT_MICROBIOTA_DYSBIOSIS["GUT MICROBIOTA DYSBIOSIS"]
GUT_MICROBIOTA_DYSBIOSIS -->|"disrupts"| gut_brain_axis["gut-brain axis"]
GUT_MICROBIOTA_DYSBIOSIS -->|"contributes to"| Systemic_Inflammation["Systemic Inflammation"]
GUT_MICROBIOTA_DYSBIOSIS -->|"involved_in"| Gut_Brain_Axis["Gut-Brain Axis"]
GUT_MICROBIOTA_DYSBIOSIS -->|"modulates"| Gastrointestinal_Permeability["Gastrointestinal Permeability"]
GUT_MICROBIOTA_DYSBIOSIS -->|"risk_factor_for"| Parkinson_S_Disease["Parkinson'S Disease"]
GUT_MICROBIOTA_DYSBIOSIS -->|"modulates"| Gastrointestinal_Motility["Gastrointestinal Motility"]
GUT_MICROBIOTA_DYSBIOSIS -->|"promotes"| Inflammation["Inflammation"]
GUT_MICROBIOTA_DYSBIOSIS -->|"contributes to"| Parkinson_s_Disease_Pathogenes["Parkinson's Disease Pathogenesis"]
Acute_Sleep_Deprivation["Acute Sleep Deprivation"] -->|"causes"| GUT_MICROBIOTA_DYSBIOSIS
Resveratrol["Resveratrol"] -.prevents.-> GUT_MICROBIOTA_DYSBIOSIS| Target | Relation | Type | Str |
|---|---|---|---|
| gut-brain axis | disrupts | pathway | 0.88 |
| Gastrointestinal Permeability | modulates | phenotype | 0.85 |
| Gastrointestinal Motility | modulates | phenotype | 0.85 |
| Gut-Brain Axis | involved_in | pathway | 0.85 |
| Alzheimer's Disease | associated_with | disease | 0.85 |
| Parkinson'S Disease | risk_factor_for | disease | 0.85 |
| Inflammation | promotes | process | 0.85 |
| Systemic Inflammation | contributes_to | process | 0.85 |
| Parkinson's Disease Pathogenesis | contributes_to | process | 0.83 |
| Amyloid-Beta Deposition | contributes_to | biomarker | 0.82 |
| Alzheimer'S Disease Progression | biomarker_for | phenotype | 0.82 |
| Circadian Dysregulation | contributes_to | process | 0.80 |
| Brain Function | modulates | phenotype | 0.80 |
| depression | risk_factor_for | disease | 0.80 |
| Parkinson's Disease | causes | disease | 0.80 |
| Anxiety | associated_with | disease | 0.80 |
| Depression | associated_with | disease | 0.80 |
| Chemotherapy-Induced Peripheral Neuropathy | associated_with | disease | 0.75 |
| Major depressive disorder | associated_with | disease | 0.70 |
| neuroinflammation | activates | process | 0.70 |
| Parkinson's disease | associated_with | disease | 0.70 |
| Major Depressive Disorder | causes | disease | 0.70 |
| leaky gut | causes | process | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Acute Sleep Deprivation | causes | process | 0.95 |
| 41694373 | exhibits significant correlation with | paper | 0.90 |
| Crocetin | protects_against | compound | 0.80 |
| Resveratrol | prevents | drug | 0.75 |
| 36761177 | might be associated with | paper | 0.60 |
| 36761177 | associated with | paper | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning GUT MICROBIOTA DYSBIOSIS in their description or question text
No additional research found