gene

DCTN2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DCTN2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

7Connections

0Hypotheses

0Analyses

4Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for DCTN2 - Dynactin Subunit 2

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🧬 Gene Info

Gene Symbol	DCTN2
Full Name	Dynactin Subunit 2
Aliases	Page for DCTN2, Page for DCTN2 Protein
Function	is a structural subunit of the dynactin complex, which acts with cytoplasmic dynein to move cargo toward microtubule minus ends.
Amino Acids	400 aa
UniProt ID	DCTN2
GeneCards	DCTN2
Human Protein Atlas	DCTN2
Associated Diseases	neurodegeneration
Interactions	ALPHA-SYNUCLEIN, GBA1, PARKINSON'S DISEASE
KG Connections	7 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

DCTN2 - Dynactin Subunit 2

gene · 677 words

→

DCTN2 Protein - Dynactin Subunit 2

protein · 626 words

→

Pathway Diagram

graph TD
    DCTN2["DCTN2"]
    Parkinson{"Parkinson"}
    DCTN2 -->|"interacts with"| Parkinson
    Als{"Als"}
    DCTN2 -->|"interacts with"| Als
    Ms{"Ms"}
    DCTN2 -->|"interacts with"| Ms
    GBA["GBA"]
    DCTN2 -->|"associated with"| GBA
    neurodegeneration["neurodegeneration"]
    DCTN2 -->|"implicated in"| neurodegeneration
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    PARKINSON_S_DISEASE -->|"interacts with"| DCTN2
    ALPHA_SYNUCLEIN["ALPHA-SYNUCLEIN"]
    ALPHA_SYNUCLEIN -->|"interacts with"| DCTN2
    GBA1["GBA1"]
    GBA1 -->|"interacts with"| DCTN2
    style DCTN2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (4)

Target	Relation	Type	Str
Parkinson	interacts_with	disease	0.65
Als	interacts_with	disease	0.65
Ms	interacts_with	disease	0.65
GBA	associated_with	gene	0.60

Incoming (3)

Source	Relation	Type	Str
GBA1	interacts_with	gene	0.60
PARKINSON'S DISEASE	interacts_with	gene	0.60
ALPHA-SYNUCLEIN	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DCTN2 in their description or question text

No additional research found