Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about COLITIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | COLITIS |
| Key Genes/Proteins | L_REUTERI |
graph TD
COLITIS[COLITIS]
STING[STING] -->|target for| COLITIS
Substance_P[Substance P] -->|treats| COLITIS
substance_P[substance P] -.protects against.-> COLITIS
AMBRA1[AMBRA1] -->|causes| COLITIS
DSS[DSS] -->|causes| COLITIS
GS_1[GS-1] -->|treats| COLITIS
P5091[P5091] -->|treats| COLITIS
ferroptosis[ferroptosis] -->|promotes| COLITIS
Fk866[Fk866] -->|treats| COLITIS| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| Substance P | associated_with | entity | 0.95 |
| STING | therapeutic_target | protein | 0.95 |
| Substance P | treats | protein | 0.95 |
| substance P | protects_against | protein | 0.90 |
| AMBRA1 | causes | protein | 0.90 |
| DSS | causes | drug | 0.90 |
| Dextran Sodium Sulfate | associated_with | compound | 0.90 |
| GS-1 | treats | compound | 0.85 |
| GS-1 | treats | compound | 0.85 |
| P5091 | treats | drug | 0.80 |
| ferroptosis | promotes | process | 0.80 |
| Fk866 | treats | drug | 0.75 |
| L_REUTERI | treats | gene | 0.72 |
| IL-6 | associated_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning COLITIS in their description or question text
No additional research found