gene

CNTNAP2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CNTNAP2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

9Connections

0Hypotheses

0Analyses

6Outgoing

3Incoming

0Experiments

0Debates

Summary

Page for CNTNAP2 — Contactin Associated Protein 2

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🧬 Gene Info

Gene Symbol	CNTNAP2
Full Name	Contactin Associated Protein 2
Chromosome	7q35
Protein Type	Gene
Function	is an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization	both presynaptic and postsynaptic membranes, where it functions as a bidirectional synaptic organizer
Molecular Weight	200 kDa
Amino Acids	901 aa
Exons	24
UniProt ID	O14520
NCBI Gene ID	26045
Ensembl ID	ENSG00000198006
GeneCards	CNTNAP2
Human Protein Atlas	CNTNAP2
Associated Diseases	Autism spectrum disorder, epilepsy, intellectual disability, Pitt-Hopkins syndrome, Alzheimer's disease, Parkinson's disease
Interactions	AND, MMP9
KG Connections	9 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CNTNAP2 — AlphaFold O14520 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CNTNAP2 — Contactin Associated Protein 2

gene · 859 words

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Contactin Associated Protein 2 (CNTNAP2 Protein)

protein · 736 words

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Pathway Diagram

flowchart TD
    CNTNAP2(["CNTNAP2"])
    Autism["Autism"]
    Als["Als"]
    MMP9(["MMP9"])
    AND(["AND"])
    neurodegeneration["neurodegeneration"]

    CNTNAP2 -.->|"inhibits"| Autism
    CNTNAP2 -.->|"inhibits"| Als
    CNTNAP2 -.->|"inhibits"| MMP9
    CNTNAP2 -.->|"inhibits"| AND
    MMP9 -.->|"inhibits"| CNTNAP2
    CNTNAP2 -->|"implicated in"| neurodegeneration

    style CNTNAP2 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (6)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:CNTNAP2	data_in	dataset_row	0.00
ds-83b31ef18d49	provides_data_for	dataset	1.00
Autism	inhibits	disease	0.65
Als	inhibits	disease	0.65
AND	inhibits	gene	0.60
MMP9	inhibits	gene	0.60

Incoming (3)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:CNTNAP2	data_in	dataset_row	0.00
ds-83b31ef18d49	data_in	dataset	1.00
MMP9	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CNTNAP2 in their description or question text

No additional research found