Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about APOPTOTIC PROTEASE ACTIVATING FACTOR 1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | APOPTOTIC PROTEASE ACTIVATING FACTOR 1 |
| Molecular Weight | 140 kDa |
| Amino Acids | 1248 aa |
| Pathways | apoptosis |
| Interactions | apaf1 |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
graph TD
APOPTOTIC_PROTEASE_ACTIVATING_FACTOR_1(["APOPTOTIC PROTEASE ACTIVATING FACTOR 1"])
apoptosis["apoptosis"]
AXON["AXON"]
NEURONS["NEURONS"]
apaf1["apaf1"]
APOPTOTIC_PROTEASE_ACTIVATING_FACTOR_1 -->|"activates"| apoptosis
APOPTOTIC_PROTEASE_ACTIVATING_FACTOR_1 -->|"activates"| AXON
APOPTOTIC_PROTEASE_ACTIVATING_FACTOR_1 -->|"activates"| NEURONS
apaf1 -->|"activates"| APOPTOTIC_PROTEASE_ACTIVATING_FACTOR_1
style APOPTOTIC_PROTEASE_ACTIVATING_FACTOR_1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
style apoptosis fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff
style AXON fill:#1a1a2e,stroke:#ffd54f,stroke-width:2px,color:#fff
style NEURONS fill:#1a1a2e,stroke:#ffd54f,stroke-width:2px,color:#fff
style apaf1 fill:#1a237e,stroke:#ce93d8,stroke-width:2px,color:#fff| Source | Relation | Type | Str |
|---|---|---|---|
| apaf1 | activates | gene | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning APOPTOTIC PROTEASE ACTIVATING FACTOR 1 in their description or question text
No additional research found