protein 713 words KG: APAF1PROTEIN
Contents

Apoptotic Protease Activating Factor 1 Protein

🔬 Protein Info
Gene SymbolAPAF1PROTEIN
Functionis an important component in the neurobiology of neurodegenerative diseases.
Subcellular Localization</th><td>Cytoplasm</td></tr>
Molecular Weight140 kDa
GeneCardsAPAF1PROTEIN
Human Protein AtlasAPAF1PROTEIN
Small molecule apoptosome inhibitorsUnder development for neuroprotection
Caspase-9 inhibitorsCould block downstream effects of APAF1 activation
BCL-2 mimeticsPrevent cytochrome c release, upstream of APAF1
Associated Diseasesneurodegenerative_diseases
InteractionsAMPK, AND, APOPTOSIS, CALR, CANX, caspase-3
KG Connections62 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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