Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about A1_ASTROCYTES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| neurotoxicity | causes | mechanism | 0.80 |
| NEUROINFLAMMATION | activates | phenotype | 0.64 |
| C3 | expressed_in | protein | 0.64 |
| CXCL10 | expressed_in | protein | 0.64 |
| NEURONAL_DEATH | activates | phenotype | 0.56 |
| Source | Relation | Type | Str |
|---|---|---|---|
| IL1A | activates | protein | 0.72 |
| C1Q | activates | protein | 0.72 |
| TNF_ALPHA | activates | protein | 0.72 |
| age | associated_with | process | 0.70 |
| IL1A/TNF/C1QA_blockade | prevents | drug | 0.70 |
| IL1A | causes | gene | 0.70 |
| TNF | causes | gene | 0.70 |
| C1QA | causes | gene | 0.70 |
| MITOCHONDRIA | activates | pathway | 0.64 |
| mTOR_inhibition | inhibits | pathway | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-01 | 0 hypotheses
neurodegeneration | 2026-04-01 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.95 · 2026-04-09
closed · Rounds: 5 · Score: 0.95 · 2026-04-01
Hypotheses and analyses mentioning A1_ASTROCYTES in their description or question text
No additional research found