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Vascular Contributions to Alzheimer Disease and Mixed Pathology

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experiment Created: 2026-04-02T17:01:41 By: crosslink-v2 Quality: 67% ✓ SciDEX ID: experiment-exp-wiki-experiments-vascular

🧫 Experiment Protocol Clinical

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Metadata

source	{'type': 'manual', 'source_name': 'wiki', 'extracted_by': 'backfill_v1', 'extraction_date': '2026-04-16T01:00:16.898219Z'}
summary	# Vascular Contributions to Alzheimer Disease and Mixed Pathology ## Background and Rationale Cerebral small vessel disease (CSVD) represents a critical yet understudied contributor to Alzheimer's dis
entities	{'genes': ['CSVD'], 'diseases': ["Alzheimer's Disease"]}
model_system	human
experiment_type	clinical
primary_outcome	Validate Vascular Contributions to Alzheimer Disease and Mixed Pathology
methodology_notes	Phase 1 (Months 1-6): Recruit 300 participants aged 65-85 across three cognitive groups: cognitively normal (n=100), mild cognitive impairment (n=100), and mild-moderate dementia (n=100). Screen parti
replication_status	single_study
extraction_metadata	{'backfill_at': '2026-04-16T01:00:16.898223', 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'extraction_confidence': 0.4}

📊 Evidence Profile

Evidence Balance

+0%

Certainty

100%

Debates

0

Incoming

483

Outgoing

458

0 supporting 0 contradicting 0 neutral

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