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bEV-mediated synaptic pruning via C1q-C3 pathway

experiment Created: 2026-04-11T05:33:25 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-a1acd0d3-8c0a-4c27-a025-0

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🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

📊 Evidence Profile

Evidence Balance

+0%

Certainty

100%

Debates

0

Incoming

22

Outgoing

23

0 supporting 0 contradicting 0 neutral

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Linked Artifacts (45)

mentions📖C3 Protein (Complement Component 3)80%

mentions📖C1Q Protein (Complement Component 1q)80%

mentions📖C3 — Complement Component 380%

mentions📖c1q80%

related📖C1Q Protein (Complement Component 1q)72%

related📖c1q72%

related📖C3 Protein (Complement Component 3)72%

mentions📖APP Mutations in Alzheimer's Disease60%

mentions📖Alzheimer's Disease vs Parkinson's Disease Compari60%

mentions📖Alzheimer's Disease60%

mentions📖Investment Landscape: Alzheimer's Disease60%

mentions📖Prodromal Alzheimer's Disease60%

mentions📖Microglia60%

mentions📖Preclinical Alzheimer's Disease60%

related📖Alzheimer's Disease60%

mentions📖mechanisms60%

mentions📖Microglia60%

mentions📖Agitation in Alzheimer's Disease60%

mentions📖Sporadic vs Familial Alzheimer's Disease: Comprehensive60%

mentions📖Alzheimer's Disease Genetic Variants60%

mentions📖PSEN2 Mutations in Alzheimer's Disease60%

mentions📖Early-Onset Alzheimer's Disease (EOAD)60%

mentions📖TREM2 Variants in Alzheimer's Disease60%

mentions📖PSEN1 Mutations in Alzheimer's Disease60%

mentions📖DLB, Parkinson's Disease, and Alzheimer's Disease:60%

related📖Investment Landscape: Alzheimer's Disease54%

related📖Prodromal Alzheimer's Disease54%

related📖PSEN1 Mutations in Alzheimer's Disease54%

related📖Alzheimer's Disease Genetic Variants54%

related📖PSEN2 Mutations in Alzheimer's Disease54%

related📖Agitation in Alzheimer's Disease54%

related📖Sporadic vs Familial Alzheimer's Disease: Comprehensive54%

related📖Early-Onset Alzheimer's Disease (EOAD)54%

related📖Alzheimer's Disease vs Parkinson's Disease Compari54%

related📖Microglia54%

related📖APP Mutations in Alzheimer's Disease54%

related📖mechanisms54%

related📖Alzheimer's Disease54%

related📖TREM2 Variants in Alzheimer's Disease54%

related📖DLB, Parkinson's Disease, and Alzheimer's Disease:54%

related📖Microglia54%

related📖Preclinical Alzheimer's Disease54%

related🧫LPS-induced mouse model of depression with synaptic loss ana33%

related📖C3 — Complement Component 333%

related📖C333%

💬 Discussion