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LPS-induced mouse model of depression with synaptic loss analysis

active
experiment Created: 2026-04-10T21:35:54 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-126e411e-2d1d-47f8-b220-3
Related Entities
C1q
🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

📊 Evidence Profile
Evidence Balance
+0%
Certainty
70%
Debates
0
Incoming
14
Outgoing
14
0 supporting 0 contradicting 0 neutral
View full evidence profile →
Linked Artifacts (24)
derives_from📄Complement C1q/C3-CR3 signaling pathway mediates abnormal mi100%
related🧫C1q neutralizing antibody intervention in depression model100%
related🧫Bidirectional Mendelian randomization analysis of C1Q and is100%
related🧫Bidirectional Mendelian randomization analysis of C1Q and is100%
mentions📖c1q90%
mentions📖c1q80%
mentions📖C1Q Protein (Complement Component 1q)80%
related📖C1Q Protein (Complement Component 1q)72%
related📖c1q72%
related📖depression70%
mentions📖CR3-Dependent Microglial Synapse Elimination in Parkinson&#x70%
related📖CR3-Dependent Microglial Synapse Elimination in Parkinson&#x63%
mentions📖Microglia60%
mentions📖researchers60%
related📖Depression (Major Depressive Disorder)60%
mentions📖Microglia60%
mentions📖Depression (Major Depressive Disorder)60%
mentions📖Dentate Gyrus60%
related📖Dentate Gyrus54%
related📖researchers54%
related📖Microglia54%
related📖Depression (Major Depressive Disorder)54%
related📖Microglia54%
related🧫bEV-mediated synaptic pruning via C1q-C3 pathway33%

💬 Discussion