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TFEB silencing and misfolded protein degradation

active

experiment Created: 2026-04-06T19:29:04 By: experiment_extractor Quality: 88% ✓ SciDEX ID: experiment-exp-2141f24c-6948-4c8b-a156-2

Related Entities

🌍 Provenance Graph 2 nodes, 1 edges

derives from (1)

experiment-exp-2141f24c-6948-4→paper-30335591

📊 Evidence Profile

Evidence Balance

+0%

Certainty

100%

Debates

0

Incoming

22

Outgoing

23

0 supporting 0 contradicting 0 neutral

View full evidence profile →

Linked Artifacts (42)

related🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling100%

derives_from📄Trehalose induces autophagy via lysosomal-mediated TFEB acti100%

related🧫Trehalose-induced lysosomal membrane permeabilization and TF100%

related🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction100%

related🧫Trehalose analog testing for autophagy induction100%

related🧫Trehalose-induced lysosomal changes and TFEB activation100%

mentions📖AtlasX Bio90%

mentions📖TFEB Activators for Parkinson's Disease80%

mentions📖tfeb-activators-neurodegeneration80%

mentions📖TFEB80%

mentions📖TFEB Protein80%

mentions📖TFEB-Mediated Lysosomal Biogenesis80%

mentions📖entities-tfeb80%

mentions📖TFEB Protein (Transcription Factor EB)80%

mentions📖TFEB Activators in Neurodegeneration80%

related📖TFEB-Mediated Lysosomal Biogenesis72%

related📖TFEB Activators for Parkinson's Disease72%

related📖entities-tfeb72%

related📖TFEB72%

related📖TFEB Activators in Neurodegeneration72%

related📖TFEB Protein (Transcription Factor EB)72%

related📖TFEB Protein72%

related📖tfeb-activators-neurodegeneration72%

mentions📖TFEB Signaling in Neurodegeneration70%

mentions📖TFEB Activator Therapies for Neurodegenerative Diseases70%

mentions📖TFEB Autophagy Pathway70%

related📖TFEB Signaling in Neurodegeneration63%

related📖TFEB Autophagy Pathway63%

related📖TFEB Activator Therapies for Neurodegenerative Diseases63%

mentions📖diseases60%

related🧪TFEB-PGC1α Mitochondrial-Lysosomal Decoupling60%

related🧫Functional validation of trehalose effects on misfolded prot60%

mentions📖researchers60%

related🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction60%

related🧫Trehalose analog testing for autophagy induction60%

related🧫Trehalose-induced lysosomal changes and TFEB activation60%

related🧫Trehalose-induced lysosomal membrane permeabilization and TF60%

related🧫Transcriptome sequencing of cardiac fibroblasts in TFEB over60%

related📖autophagy55%

related📖diseases54%

related📖researchers54%

mentions📖TFEB50%

💬 Discussion