| Gene Symbol | VDAC3 |
| Aliases | VDAC3PROTEIN |
| Subcellular Localization | </th><td>Outer mitochondrial membrane, Plasma membrane</td></tr> |
| Molecular Weight | 34 kDa |
| GeneCards | VDAC3 |
| Human Protein Atlas | VDAC3 |
| β-barrel structure | 19 β-strands forming a cylindrical barrel |
| N-terminal α-helix | Located inside the pore, involved in channel gating |
| Loop regions | External loops contain binding sites for various ligands and proteins |
| Phosphorylation | Tyrosine phosphorylation at multiple sites modulates channel activity |
| Oxidation | Reactive oxygen species (ROS) can modify cysteine residues |
| S-nitrosylation | Regulates VDAC3 function in response to nitric oxide signaling |
| ATP/ADP exchange | Facilitates cytosolic energy exchange |
| Calcium signaling | Participates in mitochondrial calcium uptake |
| Apoptosis regulation | Modulates release of cytochrome c and other pro-apoptotic factors |
| Interactions | TMX2 |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!