protein

SK4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SK4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections
0Hypotheses
0Analyses
1Outgoing
1Incoming
0Experiments
0Debates

Summary

sk4-protein

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🔬 Protein Info
Gene SymbolSK4
Protein FamilyKCNN (SK/IK) family
Molecular Weight~48 kDa (427 aa)
UniProt IDQ9UQM4
GeneCardsSK4
Human Protein AtlasSK4
Known Drugs/CompoundsFerroptosis, LAT1
KG Connections2 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING
🔮 Predicted Structure: SK4 — AlphaFold Q9UQM4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

GSK4527226 (AL101) for Early Alzheimer's Disease (NCT06079190)

clinical · 1614 words

GSK4527226 (AL101) for Early Alzheimer's Disease (NCT06079190)

clinical · 781 words

GSK4527226 (AL101) Open-Label Extension (NCT07105709)

clinical · 560 words

Pathway Diagram

graph TD
    SK4{"SK4"}
    LAT1["LAT1"]
    Parkinson_s_Disease["Parkinson's Disease"]
    Ferroptosis["Ferroptosis"]

    LAT1 -->|"binds"| SK4
    LAT1 -->|"interacts with"| SK4
    SK4 -->|"protects against"| Parkinson_s_Disease
    SK4 -->|"inhibits"| Ferroptosis

    style SK4 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
    style LAT1 fill:#1a237e,stroke:#ce93d8,stroke-width:2px,color:#fff
    style Parkinson_s_Disease fill:#3e1a1a,stroke:#ef5350,stroke-width:2px,color:#fff
    style Ferroptosis fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff

Outgoing (1)

TargetRelationTypeStr
Ferroptosisinhibitsprocess0.75

Incoming (1)

SourceRelationTypeStr
LAT1interacts_withgene0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

ExperimentTypeDiseaseScoreFeasibilityModelStatusEst. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SK4 in their description or question text

No additional research found