Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SK4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SK4 |
| Protein Family | KCNN (SK/IK) family |
| Molecular Weight | ~48 kDa (427 aa) |
| UniProt ID | Q9UQM4 |
| GeneCards | SK4 |
| Human Protein Atlas | SK4 |
| Known Drugs/Compounds | Ferroptosis, LAT1 |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SK4{"SK4"}
LAT1["LAT1"]
Parkinson_s_Disease["Parkinson's Disease"]
Ferroptosis["Ferroptosis"]
LAT1 -->|"binds"| SK4
LAT1 -->|"interacts with"| SK4
SK4 -->|"protects against"| Parkinson_s_Disease
SK4 -->|"inhibits"| Ferroptosis
style SK4 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#fff
style LAT1 fill:#1a237e,stroke:#ce93d8,stroke-width:2px,color:#fff
style Parkinson_s_Disease fill:#3e1a1a,stroke:#ef5350,stroke-width:2px,color:#fff
style Ferroptosis fill:#1a1a2e,stroke:#888,stroke-width:2px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| Ferroptosis | inhibits | process | 0.75 |
| Source | Relation | Type | Str |
|---|---|---|---|
| LAT1 | interacts_with | gene | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SK4 in their description or question text
No additional research found