gene 653 words KG: RPS18
Contents

RPS18 — Ribosomal Protein S18

🧬 Gene Info
Gene SymbolRPS18
Full NameRibosomal Protein S18
Functionencodes a conserved ribosomal protein component of the 40S small ribosomal subunit.
Subcellular LocalizationRPS18 is expressed at high levels throughout the brain, particularly in: - Pyram
GeneCardsRPS18
Human Protein AtlasRPS18
Ribosomal AssemblyRPS18 participates in the early stages of 40S subunit biogenesis in the nucleolus
Translation InitiationThe protein contributes to the formation of the pre-initiation complex (PIC) that scans mRNA for start codons
tRNA BindingRPS18 interacts with the A-site of the ribosome, facilitating tRNA accommodation during translation elongation
Quality ControlThe protein plays a role in the nonsense-mediated decay (NMD) pathway, recognizing premature termination codons
Associated DiseasesPAAD
InteractionsDDX21
KG Connections15 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

H6-V1: Aberrant eIF2α Phosphorylation Drives Mitochondrial T
Score: 0.75

Knowledge Graph (12 edges)

RPS18 downregulates SORL1
RPS18 downregulates SPOCK2
RPS18 downregulates PRSS11
RPS18 downregulates ID3
RPS18 upregulates RPS2
RPS18 upregulates RPS8
RPS18 upregulates RPL37A
RPS18 interacts_with DDX21
RPS18 participates_in CSFV
RPS18 regulates ILF3

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