| Gene Symbol | VGLUT1 |
| Aliases | Vesicular Glutamate Transporter 1 |
| Chromosome | 19q13.33 |
| Primary Expression | glutamatergic (excitatory) neurons |
| Molecular Weight | 62 kDa |
| Amino Acids | 560 aa |
| Exons | 12 |
| Pathways | Amyloid, Apoptosis |
| Ensembl ID | ENSG00000177656 |
| GeneCards | VGLUT1 |
| Human Protein Atlas | VGLUT1 |
| Arg184 (TMD4) | Forms critical contacts with the glutamate carboxylate groups |
| His128 (TMD2) | Participates in proton coupling |
| TMDs 7 and 10 | Contribute to the substrate binding pocket |
| Associated Diseases | epilepsy, excitatory neuron loss, ISCHEMIA, neurodegeneration |
| Interactions | Akt, ALZHEIMER, ALZHEIMER'S DISEASE, AND, APOE, APOE3 |
| KG Connections | 204 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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