| Gene Symbol | TUBA4A |
| Aliases | TUBA4APROTEIN |
| Function | Tuba4A Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Molecular Weight | 50 kDa |
| Amino Acids | 450 aa |
| GeneCards | TUBA4A |
| Human Protein Atlas | TUBA4A |
| N-terminal domain | GTP-binding site (essential for dimerization) |
| Intermediate domain | Taxol-binding site |
| C-terminal domain | Motor protein binding and post-translational modification sites |
| Acetylation | Lys40 acetylation marks stable microtubules |
| Tyrosination/detyrosination | Cycling between tyrosinated and glutamylated forms |
| Polyglutamylation | Long polyglutamate chains regulate motor protein binding |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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