| Gene Symbol | SLC39A8 |
| Full Name | Solute Carrier Family 39 Member 8 |
| Aliases | SLC39A8PROTEIN |
| Chromosome | 4q24 |
| Protein Type | Transporter |
| Function | SLC39A8 encodes the zinc and iron transporter protein ZIP8 (also called Zrt- and Irt-like protein 8). |
| Primary Expression | dopaminergic neurons of the substantia nigra, making it particularly relevant to Parkinson's disease pathogenesis |
| Subcellular Localization | **: Plasma membrane vs. intracellular pools |
| Amino Acids | 462 aa |
| UniProt ID | [Q9C0K1](https://www.uniprot.org/uniprot/Q9C0K1) |
| Ensembl ID | ENSG00000138821 |
| OMIM | 608732 |
| GeneCards | SLC39A8 |
| Human Protein Atlas | SLC39A8 |
| Brain | Neurons, astrocytes, and microglia |
| Associated Diseases | ALS, inflammatory bowel disease, kidney disease, neurodegeneration |
| Interactions | KCNK2 |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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