| Gene Symbol | SENP2 |
| Full Name | SUMO Specific Peptidase 2 |
| Aliases | Page for SENP2 Protein |
| Protein Type | Protease |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 68 kDa |
| Amino Acids | 589 aa |
| Pathways | Wnt |
| UniProt ID | [Q9Y2W1](https://www.uniprot.org/uniprot/Q9Y2W1) |
| GeneCards | SENP2 |
| Human Protein Atlas | SENP2 |
| N-terminal regulatory domain | Contains nuclear localization signals (NLS) and regulates substrate recognition |
| Catalytic core domain | Harbors the catalytic cysteine protease activity (Cys565) |
| C-terminal domain | Involved in protein-protein interactions and substrate binding |
| Phosphorylation | Casein kinase 2 (CK2) phosphorylation enhances SENP2 activity |
| Associated Diseases | neurodegeneration |
| Interactions | ATF3 |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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