| Gene Symbol | RAB8A |
| Full Name | RAB8A Protein (Ras-Related Protein) |
| Aliases | Ras-Related Protein |
| Chromosome | 19p13.2 |
| Function | RAB8A encodes a member of the Rab GTPase family, which are key regulators of intracellular vesicle trafficking |
| Molecular Weight | 24 kDa |
| Pathways | Cholesterol |
| UniProt ID | P61006 |
| NCBI Gene ID | 51528 |
| Ensembl ID | ENSG00000135569 |
| OMIM | 608030 |
| GeneCards | RAB8A |
| Human Protein Atlas | RAB8A |
| GTP-binding domain | Classic Rossmann fold that binds GTP/GDP |
| Switch I region | Conformational change between active (GTP) and inactive (GDP) states |
| Associated Diseases | neurodegeneration |
| Interactions | ALS, AMYOTROPHIC LATERAL SCLEROSIS, AND, App, C9ORF72, C9Orf72-Smcr8 |
| KG Connections | 59 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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