| Gene Symbol | PDE10A |
| Full Name | Phosphodiesterase 10A |
| Aliases | PDE10APROTEIN |
| Function | PDE10A has unique substrate specificity |
| Primary Expression | striatum, affected in HD |
| Subcellular Localization | ** | Cytosol | |
| Pathways | Apoptosis |
| UniProt ID | O76074 |
| Ensembl ID | ENSG00000112541 |
| GeneCards | PDE10A |
| Human Protein Atlas | PDE10A |
| N-terminal regulatory region | Contains phosphorylation sites |
| GAF domain | cGMP-binding domain (non-functional in PDE10A) |
| Catalytic domain | C-terminal hydrolase domain |
| cAMP | Primary substrate |
| Associated Diseases | neurodegeneration |
| Known Drugs/Compounds | TP-10 |
| Interactions | APOPTOSIS, CANCER, DNA, MITOCHONDRIAL DYSFUNCTION |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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