protein 1,114 words KG: P2X7RECEPTOR
Contents

P2X7 Receptor Protein

🔬 Protein Info
Gene SymbolP2X7RECEPTOR
Full NameP2X7 Receptor
Protein FamilyP2X purinergic receptor family
Protein TypeChannel
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionmicroglia and immune cells and is a therapeutic target for neuroinflammatory diseases
Molecular Weight66 kDa (monomer)
Amino Acids200 aa
UniProt IDQ99572
GeneCardsP2X7RECEPTOR
Human Protein AtlasP2X7RECEPTOR
Associated Diseasesneurodegeneration
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (9)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.84
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Purinergic Signaling Polarization Control
Score: 0.71
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (4)

P2rx7 congenic mouse model insulin tolerance testing
validation · proposed · Score: 0.90
P2rx7 congenic mouse model glucose tolerance testing
validation · proposed · Score: 0.90
Gap Junction Dysfunction Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
Purinergic Signaling Dysfunction Validation in Parkinson's D
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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