| Gene Symbol | P19589 |
| Protein Family | Serine/Threonine Kinase (PKR family) |
| Protein Type | Kinase |
| Function | is a serine/threonine protein kinase that plays a central role in the cellular stress response, particularly in antiviral defense and translational control[@b愛德华茲2020]. |
| Primary Expression | Ubiquitous, high in brain |
| Subcellular Localization | Cytoplasm, nucleus |
| Molecular Weight | ~62 kDa |
| UniProt ID | P19589 |
| GeneCards | P19589 |
| Human Protein Atlas | P19589 |
| Zinc finger domain | Involved in protein-protein interactions |
| Regulatory motifs | Control kinase activation |
| Kinase subdomain XI | Contains the catalytic site |
| Activation loop | Phosphorylation site (Thr446) |
| ATP-binding pocket | Target of small molecule inhibitors |
| Associated Diseases | neurodegeneration |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!