protein 1,324 words KG: NDUFAF1
Contents

NDUFAF1 Protein

🔬 Protein Info
Gene SymbolNDUFAF1
Chromosome16p13.3
Protein FamilyAIM (Ancestral Immune Protein) family
Functionis a nuclear-encoded mitochondrial protein that plays a critical role in the biogenesis of mitochondrial Complex I, the largest enzyme of the electron transport chain.
Primary ExpressionBrain, heart, skeletal muscle, liver, kidney
Subcellular LocalizationMitochondrial matrix
Molecular Weight46 kDa
Amino Acids90 aa
UniProt ID[Q9P032](https://www.uniprot.org/uniprot/Q9P032)
Ensembl IDENSG00000166068
GeneCardsNDUFAF1
Human Protein AtlasNDUFAF1
Associated DiseasesMs
KG Connections15 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (8)

Neurodegeneration
disease · KG edge: implicated_in
BNIP3 Gene
gene · KG edge: associated_with
MCC Gene
gene · KG edge: associated_with
Mitofusin 1 (MFN1)
gene · KG edge: associated_with
NBR1 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

BNIP3 associated_with NDUFAF1
MFN1 associated_with NDUFAF1
NDUFAF7 associated_with NDUFAF1
NBR1 associated_with NDUFAF1
MCC associated_with NDUFAF1
NDUFAF1 associated_with MFN1
NDUFAF1 associated_with NBR1
NDUFAF1 associated_with BNIP3
NDUFAF1 associated_with MCC
NDUFAF1 associated_with NDUFAF7

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