| Gene Symbol | MUNC181 |
| Aliases | MUNC181PROTEIN |
| Chromosome | 9q34.3 |
| Function | is a critical presynaptic protein that plays an essential role in neurotransmitter release and synaptic vesicle trafficking. |
| Molecular Weight | 66 kDa |
| Amino Acids | 594 aa |
| Exons | 20 |
| GeneCards | MUNC181 |
| Human Protein Atlas | MUNC181 |
| Phosphorylation | Multiple serine/threonine phosphorylation sites have been identified, with CaMKII-mediated phosphorylation enhancing synaptic vesicle release probability chen2019. |
| Palmitoylation | A dynamic palmitoylation cycle regulates Munc18-1 localization to the presynaptic membrane. |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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