| Gene Symbol | MPZ |
| Full Name | Myelin Protein Zero |
| Chromosome | 1q23.3 |
| Function | The MPZ gene encodes myelin protein zero (also known as P0), a critical structural protein of the peripheral nervous system myelin sheath. |
| Primary Expression | Peripheral nervous system, Schwann cells |
| UniProt ID | P07846 |
| NCBI Gene ID | 4240 |
| Ensembl ID | ENSG00000156675 |
| OMIM | 159440 |
| GeneCards | MPZ |
| Human Protein Atlas | MPZ |
| Extracellular Ig Domain | N-terminal immunoglobulin-like domain for homophilic adhesion |
| Single Transmembrane Domain | Anchors protein in the myelin membrane |
| Intracellular C-terminus | Cytoplasmic domain involved in myelin compaction |
| Molecular weight | Approximately 27 kDa |
| Associated Diseases | Charcot-Marie-Tooth Disease, Dejerine-Sottas Syndrome |
| Interactions | Arf proteins, DAF-18, MBP, PMP22, SHP-2 |
| KG Connections | 22 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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