protein 785 words KG: LRP8APOER2PROTEIN
Contents

LRP8 (ApoER2) Protein

🔬 Protein Info
Gene SymbolLRP8APOER2
AliasesLRP8APOER2PROTEIN
FunctionLRP8 (also known as ApoER2 or apolipoprotein E receptor 2) is a member of the LDL receptor family that plays crucial roles in synaptic function, Reelin signaling, and neuronal migration.
GeneCardsLRP8APOER2
Human Protein AtlasLRP8APOER2
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Related Hypotheses (14)

APOE Isoform Expression Across Glial Subtypes
Score: 0.74
Cholesterol-CRISPR Convergence Therapy for Neurodegeneration
Score: 0.62
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76

Related Analyses (10)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completed
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived

Related Experiments (7)

AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40
AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40
Biomarker-Guided Sequential Therapy Selection in Alzheimer's
clinical · proposed · Score: 0.40
Blood-Based Biomarker Panel for Early AD Detection
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (15)

LX1001 Phase 1/2 Trial (NCT03634007) - Gene Therapy for
clinical · Pages share 9 hypotheses
LX1001 Long-Term Follow-up (NCT05400330) - Gene Therapy
clinical · Pages share 9 hypotheses
ALA-enriched Nutrition for APOE4 Carriers with MCI (NCT
clinical · Pages share 9 hypotheses
APOE3 (Apolipoprotein E3)
disease · Pages share 8 hypotheses
APOE4 (Apolipoprotein E4)
disease · Pages share 8 hypotheses

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