| Gene Symbol | KCNE3 |
| Aliases | MinK-related peptide 3 |
| Chromosome | 11p15.5 |
| Protein Type | Gene |
| Function | is a critical regulatory subunit that modulates the function of various voltage-gated potassium (Kv) channels. |
| Primary Expression | both cardiac and neuronal tissues, where it plays crucial roles in regulating excitability |
| Molecular Weight | 19 kDa |
| Amino Acids | 179 aa |
| Exons | 3 |
| UniProt ID | Q9NP86 |
| NCBI Gene ID | 10088 |
| GeneCards | KCNE3 |
| Human Protein Atlas | KCNE3 |
| KCNQ1/KCNE3 channels | Generate slowly activating, non-inactivating currents that contribute to the M-current, a key regulator of neuronal excitability |
| Voltage dependence | Shifts activation to more negative potentials, making channels more responsive at resting membrane potentials |
| Associated Diseases | neurodegeneration |
| Interactions | KCNQ1 |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!