| Gene Symbol | KANSL1 |
| Full Name | KAT8 Regulatory NSL Complex Subunit 1 |
| Chromosome | 17q21.31 |
| Function | The complex acetylates histone H4K16, a modification critical for chromatin decompaction and transcriptional activation[@cai2010]. |
| Primary Expression | the adult brain with highest levels in the cortex (particularly frontal and temporal lobes) |
| Subcellular Localization | ** | Nucleus, cytoplasm | |
| Molecular Weight | 121 kDa |
| Amino Acids | 105 aa |
| Exons | 16 |
| Pathways | Mitophagy |
| UniProt ID | Q7Z3B3 |
| NCBI Gene ID | 284058 |
| Ensembl ID | ENSG00000120071 |
| OMIM | 612452 |
| GeneCards | KANSL1 |
| Human Protein Atlas | KANSL1 |
| Associated Diseases | Alzheimer's disease, Neurodegeneration, Parkinson |
| Interactions | APOE, MAPT |
| KG Connections | 21 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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