| Gene Symbol | GCLMPROTEIN |
| Full Name | Glutamate-Cysteine Ligase Modifier Subunit |
| Chromosome | 1p22.1 |
| Protein Family | GCL family |
| Function | is a critical regulatory component in the glutathione biosynthesis pathway, playing a vital role in cellular antioxidant defense. |
| Molecular Weight | 31 kDa |
| Amino Acids | 274 aa |
| UniProt ID | P48507 |
| GeneCards | GCLMPROTEIN |
| Human Protein Atlas | GCLMPROTEIN |
| N-terminal domain | Interacts with GCLC (catalytic subunit) |
| Regulatory domain | Contains binding sites for glutathione feedback inhibition |
| Dimerization interface | Forms heterodimer with GCLC |
| Post-translational modification sites | Phosphorylation and oxidation affect function |
| Associated Diseases | Infection, Inflammation, Sepsis |
| Interactions | GCLC, NRF2 |
| KG Connections | 53 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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