protein 620 words KG: FERRITINPROTEIN
Contents

FTH1 Protein — Ferritin Heavy Chain

🔬 Protein Info
Gene SymbolFERRITIN
AliasesFERRITINPROTEIN
Molecular Weight~21 kDa per subunit
Length183 amino acids per subunit
Quaternary Structure24-mer shell (12 Heavy + 12 Light typically)
LocationCytosol, nucleus, mitochondria
Ferroxidase CenterConverts Fe2+ to Fe3+ for safe storage
Iron CoreCan store up to 4500 iron atoms
Nanocage ArchitectureHollow sphere allowing iron storage
[Neurons](/entities/neurons)High expression in dopaminergic neurons
[Astrocytes](/entities/astrocytes)Iron storage in glial cells
Associated DiseasesIschemia, Als, Cancer, Ferroptosis, Neurodegeneration, Parkinson
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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