| Gene Symbol | CYP27A1 |
| Aliases | CYP27A1PROTEIN |
| Protein Type | Enzyme |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | multiple tissues: |
| Subcellular Localization | </td><td>Mitochondrial inner membrane</td></tr> |
| Molecular Weight | 60 kDa |
| Amino Acids | 503 aa |
| Pathways | Lipid Metabolism |
| Ensembl ID | ENSG00000135929 |
| GeneCards | CYP27A1 |
| Human Protein Atlas | CYP27A1 |
| N-terminal transmembrane helix | A hydrophobic anchor that localizes the protein to the inner mitochondrial membrane |
| P450 heme domain | The catalytic core containing heme iron (Fe) that binds molecular oxygen for oxidation reactions |
| Substrate-binding pocket | A hydrophobic cavity that recognizes cholesterol and sterol intermediates |
| Associated Diseases | neurodegeneration |
| Interactions | CYP46A1, CYP7B1 |
| KG Connections | 24 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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