| Gene Symbol | CHOLINEACETYLTRANSFERASE |
| Aliases | CHOLINEACETYLTRANSFERASE |
| Chromosome | 10q11.23 |
| Function | - Loss of cholinergic neurons in the pedunculopontine nucleus contributes to gait freezing |
| Subcellular Localization | the cytosol of cholinergic nerve terminals, where it packages acetylcholine into synaptic vesicles for release at the sy |
| Molecular weight | ~82 kDa |
| Primary structure | 748 amino acids |
| Subcellular localization | Cytosolic, with enrichment in nerve terminal cytoplasm |
| Enzyme classification | EC 2.3.1.6 (acetyltransferase) |
| Central nervous system | Basal forebrain nuclei (nucleus basalis of Meynert, medial septum, diagonal band), striatal interneurons, brainstem motor nuclei |
| Peripheral nervous system | Spinal cord ventral horn motor neurons, autonomic ganglia, parasympathetic neurons |
| Non-neuronal tissues | Some immune cells, endothelial cells |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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