| Gene Symbol | CHCHD3 |
| Full Name | Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 |
| Aliases | CHCHD3PROTEIN |
| Function | CHCHD3 encodes a mitochondrial protein containing twin coiled-coil helix (CHCH) domains. |
| Amino Acids | 450 aa |
| UniProt ID | CHCHD3 |
| Ensembl ID | ENSG00000165237 |
| GeneCards | CHCHD3 |
| Human Protein Atlas | CHCHD3 |
| Coiled-coil domains | Two alpha-helical coiled-coil regions that mediate protein-protein interactions |
| Twin CX9C motif | Conserved cysteine-rich sequences that coordinate zinc ions and enable protein interactions |
| C-terminal inner membrane anchor | Facilitates localization to the mitochondrial inner membrane |
| Cristae junctions | Form and maintain contact sites between cristae and inner membrane |
| Cristae spacing | Regulates the distance and architecture of cristae folds |
| ATP synthase interaction | Coordinates with ATP synthase dimerization for optimal ATP production[-@s2008] |
| Associated Diseases | neurodegeneration |
| Interactions | RB1CC1 |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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