protein 819 words KG: C4APROTEIN
Contents

C4A Protein (Complement Component 4A)

🔬 Protein Info
Gene SymbolC4A
Full NameComplement Component 4A (Chido/Rodgers Blood Group)
AliasesComplement component C4A gene, Complement Component 4A
Chromosome6p21.3
Functionencodes a critical protein in the classical complement cascade, a key component of the innate immune system.
Molecular Weight104 kDa
Amino Acids1741 aa
UniProt IDP0C0P0
NCBI Gene ID712
Ensembl IDENSG00000144711
OMIM120810
GeneCardsC4A
Human Protein AtlasC4A
Associated DiseasesAls
InteractionsC4, C4B, PSP
KG Connections34 knowledge graph edges
DatabasesGeneCardsHPASTRING

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UniProtWikipedia

Related Hypotheses (11)

...
Score: 0.68
Complement C1QA Spatial Gradient in Cortical Layers
Score: 0.68
Complement-Mediated Synaptic Pruning Dysregulation
Score: 0.61
Selective HDAC3 Inhibition with Cognitive Enhancement
Score: 0.78
HDAC3-Selective Inhibition for Clock Reset
Score: 0.71
SASP-Mediated Complement Cascade Amplification
Score: 0.70
Complement C1q Mimetic Decoy Therapy
Score: 0.69
Complement C1q Subtype Switching
Score: 0.66
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62

Related Analyses (11)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Key Papers (1)

Schizophrenia risk from complex variation of complement component 4.
Nature 2016

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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