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mechanism 1,253 words KG: neuromelanin
Contents

Neuromelanin Loss in Progressive Supranuclear Palsy

⚙ Mechanism Info
Nameneuromelanin
Key Genes/Proteinsp62 inclusions, ubiquitin inclusions
Related Diseasessubstantia nigra vulnerability

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🌐 Cross-references

Wikipedia

Related Hypotheses (2)

Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51

Related Analyses (27)

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Related Experiments (22)

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clinical · proposed · Score: 0.40Sporadic ALS Initiation Biology: Deep Phenotyping of At-Risk
clinical · proposed · Score: 0.40

See Also (1)

dopaminergic-neurons
general · KG edge: expressed_in

Knowledge Graph (5 edges)

neuromelanin expressed_in dopaminergic_neurons
neuromelanin causes p62 inclusions
neuromelanin causes ubiquitin inclusions
iron modulates neuromelanin
neuromelanin associated_with substantia nigra vulnerability

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