gene 1,812 words KG: VGLUT1
Contents

VGLUT1 Gene

🧬 Gene Info
Gene SymbolVGLUT1
AliasesVesicular Glutamate Transporter 1
Chromosome19q13.33
Primary Expressionglutamatergic (excitatory) neurons
Molecular Weight62 kDa
Amino Acids560 aa
Exons12
PathwaysAmyloid, Apoptosis
Ensembl IDENSG00000177656
GeneCardsVGLUT1
Human Protein AtlasVGLUT1
Cerebral cortexHighest in layers II-III and V (pyramidal neurons)
HippocampusCA1-CA3 pyramidal cells, dentate gyrus granule cells
Olfactory bulbMitral and tufted cells
ThalamusSpecific relay nuclei
Associated Diseasesepilepsy, excitatory neuron loss, ISCHEMIA, neurodegeneration
InteractionsAkt, ALZHEIMER, ALZHEIMER'S DISEASE, APOE, APOE3, APOE4
KG Connections198 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

VGLUT1 associated_with LAMP1
VGLUT1 encoded_by SLC17A7
VGLUT1 localized_to SYNAPTIC_VESICLE
VGLUT1 pharmacological_target TRORILUZOLE
VGLUT1 activates TAU
VGLUT1 activates APOE
VGLUT1 activates APOE4
VGLUT1 activates VEGF
VGLUT1 activates GFAP
VGLUT1 associated_with VGLUT2

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