| Gene Symbol | TRA2B |
| Full Name | Transformer 2 Beta Homolog |
| Aliases | Transformer-2 beta |
| Chromosome | 3q27.2 |
| Function | TRA2B functions as a sequence-specific RNA-binding protein that promotes exon inclusion during pre-mRNA splicing. |
| Molecular Weight | 33 kDa |
| Amino Acids | 288 aa |
| UniProt ID | [Q13595](https://www.uniprot.org/uniprot/Q13595) |
| Ensembl ID | ENSG00000161940 |
| OMIM | 605200 |
| GeneCards | TRA2B |
| Human Protein Atlas | TRA2B |
| Exon Recognition | TRA2B binds to exonic splicing enhancers (ESEs), helping the spliceosome identify correct splice sites |
| Alternative Splicing Regulation | Controls inclusion/exclusion of alternatively spliced exons in neuronal transcripts |
| Neuronal Transcriptome Diversity | Generates splice variants essential for neuronal function |
| Associated Diseases | Alzheimer's disease, Parkinson's disease, ALS |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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