| Gene Symbol | RPL18A |
| Function | encodes a ribosomal protein component of the 60S large ribosomal subunit. |
| Molecular Weight | 20 kDa |
| Amino Acids | 176 aa |
| Ensembl ID | ENSG00000105640 |
| GeneCards | RPL18A |
| Human Protein Atlas | RPL18A |
| Protein synthesis | Contributes to peptide bond formation at the peptidyl transferase center |
| Ribosome assembly | Essential for proper 60S subunit biogenesis |
| rRNA interaction | Interacts with 28S rRNA to stabilize the large subunit |
| Translation termination | Participates in the release factor binding site |
| Subunit association | Critical for proper 60S assembly and 80S ribosome formation |
| N-terminal domain | Contains RNA-binding regions |
| Central region | Involved in protein-protein interactions with other ribosomal proteins |
| Surface localization | Positioned to interact with both ribosomal components and extraribosomal factors |
| Associated Diseases | Aortic Valve Calcification, Salivary Gland Damage |
| KG Connections | 3 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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