gene 1,871 words KG: PPID
Contents

PPID — Peptidylprolyl Isomerase D

🧬 Gene Info
Gene SymbolPPID
Full NamePeptidylprolyl Isomerase D
Aliasescyclophilin D
Chromosome4q31.3
Protein TypeChannel
Functionis a nuclear-encoded mitochondrial cyclophilin protein that plays a critical role in regulating the mitochondrial permeability transition pore (mPTP).
Primary Expressionall major neuronal populations in the cerebral cortex, hippocampus, basal ganglia, cerebellum, and brainstem [9]
Molecular Weight41 kDa
Amino Acids323 aa
UniProt IDQ8WWC6
NCBI Gene ID54840
Ensembl IDENSG00000117595
GeneCardsPPID
Human Protein AtlasPPID
PPIase domainCatalyzes cis-trans isomerization of peptidyl-prolyl bonds
Associated DiseasesAlzheimer's disease, Parkinson's disease
KG Connections1 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

Prohibitin-2 Mitochondrial Cross-Seeding Hub Disruption
Score: 0.47

Related Analyses (1)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (13)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

Knowledge Graph (1 edges)

genes-ppid linked_to PPID

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