gene 848 words KG: PLOR
Contents

PLOR1 Gene

🧬 Gene Info
Gene SymbolPLOR
Full NamePLOR1 (Phospholipid Remodeling protein)
Chromosome19q13.32
Protein TypeEnzyme
Functionplays important roles in cellular homeostasis, protein quality control, and signal transduction
Primary Expressionvarious brain regions with particular enrichment in areas affected in neurodegenerative diseases:
UniProt IDQ8IV08
NCBI Gene ID614739
Ensembl IDENSG00000105223
OMIM614739
GeneCardsPLOR
Human Protein AtlasPLOR
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (150)

TREM2-Dependent Microglial Senescence Transition
Score: 0.62
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62
SIRT6-NAD+ Axis Enhancement Therapy
Score: 0.61
Complement-Mediated Synaptic Pruning Dysregulation
Score: 0.61
The Glial Ketone Metabolic Shunt Hypothesis
Score: 0.61
LRP1-Dependent Tau Uptake Disruption
Score: 0.60
Glycosaminoglycan Template Disruption Approach
Score: 0.60
Netrin-1 Gradient Restoration
Score: 0.59
VCP-Mediated Autophagy Enhancement
Score: 0.59
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.56
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Miro1-Mediated Mitochondrial Trafficking Enhancement Therapy
Score: 0.55
Temporal Decoupling via Circadian Clock Reset
Score: 0.54
Lysosomal Membrane Repair Enhancement
Score: 0.54
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
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Related Analyses (30)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in

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